Mean Corpuscular Volume (MCV)
Mean Corpuscular Volume (MCV) explained
Mean Corpuscular Volume (MCV) is a component of the CBC used to refine evaluation of anemia, infection, inflammation, and bleeding risk.
Varies by laboratory (LDT/CLIA; not FDA‑approved as a drug)Mean Corpuscular Volume (MCV) helps treat
• Anemia classification/refinement
• Infection/inflammation clues
• Bleeding/clotting context
additional medications
• Related clinical evaluation and history
• Repeat testing to confirm abnormal results
• Additional targeted labs as recommended
medication risks
• False positives/negatives leading to unnecessary anxiety or missed diagnoses
• Privacy and insurance implications depending on results
• Pre‑analytical variables (fasting, meds) can affect accuracy
side effects
• Bruising or soreness at draw site
• Lightheadedness or fainting (rare)
• Infection at puncture site (very rare)
FAQs
Q: Fasting?A: Not required.
Q: What alters values?
A: Hydration, altitude, pregnancy, medications.
Q: Trends?
A: Serial measurements aid interpretation.
Q: Next tests?
A: Iron, B12/folate, smear, or bone marrow in select cases.
Q: Insurance?
A: Covered when indicated.
