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Magnesium (glycinate or L‑threonate) explained

Magnesium (especially glycinate or L‑threonate) is a mineral supplement used to support sleep quality, stress response, muscle and nerve function, and overall relaxation.

Not FDA Approved

Magnesium (glycinate or L‑threonate) helps treat

• Sleep quality and latency (may support)
• Stress resilience and relaxation
• Muscle cramps/twitches from low magnesium
• Headache/migraine support
• Constipation support (other forms like citrate)
• Blood pressure support in deficiency
• Glucose metabolism (when low)
• Bone health (with vitamin D and calcium)


additional medications

• Sleep hygiene/CBT‑I for sleep
• Electrolyte repletion via diet (leafy greens, nuts)
• Melatonin or glycine at bedtime

medication risks

• Can reduce absorption of certain medications if taken together
• Caution in significant kidney disease (risk of high magnesium)

side effects

• Loose stools (esp. citrate/oxide)
• Nausea
• Abdominal cramping

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FAQs

Q: Is magnesium FDA‑approved to treat conditions?
A: No—dietary supplements aren’t FDA‑approved to treat or prevent disease in the U.S.

Q: Which forms are gentlest?
A: Glycinate is typically gentle on the stomach; L‑threonate is marketed for cognitive support.

Q: When should I take it?
A: Often in the evening for sleep support; separate from some meds that bind minerals.

Q: Any interactions?
A: May interact with some antibiotics, thyroid meds, and bisphosphonates—separate dosing times.

Q: How fast will I notice effects?
A: Varies; sleep and muscle comfort may improve within days to weeks if you were low.

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