Alanine Transaminase (ALT) / Aspartate Transaminase (AST)
Alanine Transaminase (ALT) / Aspartate Transaminase (AST) explained
ALT and AST are liver enzymes used to assess liver injury or inflammation.
Varies by laboratory (LDT/CLIA; not FDA‑approved as a drug)Alanine Transaminase (ALT) / Aspartate Transaminase (AST) helps treat
• Screening for liver disease
• Medication monitoring
• Workout or muscle injury context (AST)
additional medications
• Related clinical evaluation and history
• Repeat testing to confirm abnormal results
• Additional targeted labs as recommended
medication risks
• False positives/negatives leading to unnecessary anxiety or missed diagnoses
• Privacy and insurance implications depending on results
• Pre‑analytical variables (fasting, meds) can affect accuracy
side effects
• Bruising or soreness at draw site
• Lightheadedness or fainting (rare)
• Infection at puncture site (very rare)
FAQs
Q: Fasting?A: Not required.
Q: Exercise effect?
A: Strenuous exercise can raise AST transiently.
Q: Alcohol/meds?
A: Alcohol and drugs can elevate enzymes.
Q: Next steps?
A: Repeat and add hepatitis panel or imaging as indicated.
Q: Insurance?
A: Covered when indicated.
