Citalopram (Celexa)
Citalopram (Celexa) explained
Citalopram (Celexa) is an SSRI primarily approved for major depressive disorder. It’s known for simple dosing but carries a dose‑dependent QT prolongation warning requiring caution at higher doses.
FDA ApprovedCitalopram (Celexa) helps treat
• Major depressive disorder (MDD)
• Generalized anxiety disorder (off‑label)
• Panic disorder (off‑label)
• Social anxiety disorder (off‑label)
• Obsessive–compulsive disorder (off‑label)
• Post‑traumatic stress disorder (off‑label)
• Premenstrual dysphoric disorder (off‑label)
additional medications
• Other SSRIs (escitalopram, sertraline, fluoxetine, paroxetine)
• SNRIs (venlafaxine, duloxetine)
• Bupropion, mirtazapine
• Psychotherapy (CBT)
medication risks
• Black box warning: suicidality risk in young people
• Dose‑dependent QT prolongation
• Serotonin syndrome risk
• Hyponatremia/SIADH
• Bleeding risk with NSAIDs/anticoagulants
• Activation of mania/hypomania in bipolar disorder
side effects
• Nausea
• Insomnia or somnolence
• Sexual dysfunction
• Dry mouth, sweating
• Tremor
• Dizziness, headache
FAQs
Q: What is citalopram used for?A: Approved for MDD; often used off‑label for several anxiety disorders.
Q: Why is there a dose limit?
A: Higher doses increase QT prolongation risk; many patients are limited to 40 mg/day or less.
Q: Can I combine with other antidepressants?
A: Only with medical supervision due to serotonin syndrome risk.
Q: Does it cause sexual side effects?
A: Yes, similar to other SSRIs.
Q: How long to see results?
A: Typically 2–4 weeks for initial improvement, up to 6–8 for full effect.
