Fluoxetine (Prozac)
Fluoxetine (Prozac) explained
Fluoxetine (Prozac) is an SSRI used for depression, OCD, panic disorder, bulimia nervosa, and PMDD. It has a long half‑life, which can ease tapering and reduce withdrawal symptoms.
FDA ApprovedFluoxetine (Prozac) helps treat
• Major depressive disorder (MDD)
• Obsessive–compulsive disorder (OCD)
• Panic disorder
• Bulimia nervosa
• Premenstrual dysphoric disorder (PMDD)
• Post‑traumatic stress disorder (off‑label)
• Social anxiety disorder (off‑label)
• Generalized anxiety disorder (off‑label)
additional medications
• Other SSRIs (sertraline, citalopram, escitalopram, paroxetine)
• SNRIs (venlafaxine, duloxetine)
• Bupropion, mirtazapine
• Psychotherapy (CBT)
medication risks
• Black box warning: suicidality risk in young people
• Serotonin syndrome risk
• Bleeding risk with NSAIDs/anticoagulants
• Hyponatremia/SIADH
• Angle‑closure glaucoma risk in susceptible patients
• Activation of mania/hypomania in bipolar disorder
side effects
• Nausea, diarrhea
• Insomnia, nervousness
• Headache
• Sexual dysfunction
• Sweating, tremor
• Dry mouth
FAQs
Q: What is fluoxetine used for?A: MDD, OCD, panic disorder, bulimia, and PMDD.
Q: How long does fluoxetine stay in the body?
A: It has a long half‑life; active metabolite norfluoxetine can persist for weeks.
Q: Can I take fluoxetine with other antidepressants?
A: Only under medical guidance to avoid interactions, especially serotonin syndrome.
Q: Does it cause weight changes?
A: Weight loss early on is possible; weight changes vary by person.
Q: Can fluoxetine be combined with olanzapine?
A: Yes, as a separate combo product for treatment‑resistant depression or bipolar depression—prescribed by clinicians.
