Glycine
Glycine explained
Glycine is a simple amino acid used at bedtime to promote deeper, cooler sleep and next‑day alertness in some studies.
Not FDA ApprovedGlycine helps treat
• Sleep quality and latency (may support)
• Core temperature regulation at night
• Calm and relaxation
additional medications
• CBT‑I
• Melatonin
• Magnesium
medication risks
• Additive sedation with other sleep aids (theoretical)
• Caution if on multiple CNS depressants
side effects
• GI upset
• Nausea
• Soft stools
FAQs
Q: When to take?A: 30–60 minutes before bed, often 3 g in studies.
Q: Is it sedating?
A: Usually gentle; many feel refreshed rather than groggy.
Q: Interactions?
A: Few known; check if using multiple sedatives.
Q: FDA approval?
A: No—supplements aren’t FDA‑approved to treat disease.
Q: Combine with?
A: Magnesium or L‑theanine for sleep routines.