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Lamotrigine (Lamictal) explained

Lamotrigine (Lamictal) is an anticonvulsant and mood stabilizer used for seizures and bipolar I maintenance (especially depression prevention); requires slow titration to lower rash risk.

FDA Approved

Lamotrigine (Lamictal) helps treat

• Focal seizures
• Generalized seizures
• Lennox‑Gastaut syndrome
• Bipolar I maintenance (depression prevention)


additional medications

• Lithium
• Quetiapine
• Lurasidone
• Valproate (depending on phase)

medication risks

• Serious rash (SJS/TEN)
• Aseptic meningitis (rare)
• Hypersensitivity reactions

side effects

• Rash
• Headache
• Dizziness
• Nausea
• Insomnia
• Blurred vision

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FAQs

Q: Why slow titration?
A: Reduces risk of serious rash including SJS/TEN.

Q: Does it help mania?
A: Better at preventing bipolar depression than acute mania.

Q: Interactions?
A: Valproate increases levels; adjust dose.

Q: Pregnancy?
A: Discuss risks/benefits with clinician.

Q: Monitoring?
A: Watch for rash, mood, and drug interactions.

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