Palmitoylethanolamide (PEA)
Palmitoylethanolamide (PEA) explained
Palmitoylethanolamide (PEA) is an endocannabinoid‑like lipid used for nerve discomfort and inflammatory balance; evidence is growing but variable.
Not FDA ApprovedPalmitoylethanolamide (PEA) helps treat
• Neuropathic discomfort (adjunct)
• Pelvic pain syndromes (limited evidence)
• Inflammation balance
additional medications
• Medical pain management as prescribed
• Omega‑3s
• Curcumin
medication risks
• Unknown long‑term safety
• Potential interactions not fully characterized
side effects
• GI upset
• Headache
• Sleepiness
FAQs
Q: Timing?A: With meals to improve absorption and GI tolerance.
Q: Interactions?
A: Generally minimal; still discuss with a clinician.
Q: Onset?
A: May require weeks of steady use.
Q: FDA approval?
A: No—supplements aren’t FDA‑approved to treat disease.
Q: Formulations?
A: Micronized/ultra‑micronized forms aim to improve absorption.
