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Venlafaxine (Effexor XR) explained

Venlafaxine (Effexor XR) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used for depression and several anxiety disorders. The XR form allows once‑daily dosing.

FDA Approved

Venlafaxine (Effexor XR) helps treat

• Major depressive disorder (MDD)
• Generalized anxiety disorder (GAD)
• Social anxiety disorder
• Panic disorder


additional medications

• Other SNRIs (duloxetine, desvenlafaxine)
• SSRIs (sertraline, fluoxetine, escitalopram)
• Bupropion, mirtazapine
• Psychotherapy (CBT)

medication risks

• Black box warning: suicidality risk in young people
• Serotonin syndrome risk
• Elevated blood pressure/heart rate
• Discontinuation syndrome if stopped suddenly
• Angle‑closure glaucoma risk in susceptible patients

side effects

• Nausea, dizziness
• Sweating
• Insomnia or somnolence
• Dry mouth
• Constipation
• Decreased appetite

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FAQs

Q: What is venlafaxine used for?
A: MDD, GAD, social anxiety disorder, and panic disorder.

Q: Can I stop it abruptly?
A: No; taper to avoid discontinuation symptoms like dizziness and ‘brain zaps’.

Q: Does venlafaxine raise blood pressure?
A: It can; periodic monitoring is recommended.

Q: Are there interactions?
A: Yes—MAOIs and other serotonergic drugs increase serotonin syndrome risk.

Q: What if I miss a dose?
A: Take it when remembered the same day; skip if close to next dose—do not double.

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