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Vitamin B3 (niacin) explained

Vitamin B3 (niacin/niacinamide) supports energy metabolism and skin health; high‑dose niacin as a drug treats dyslipidemia under medical care.

Not FDA Approved

Vitamin B3 (niacin) helps treat

• Niacin deficiency (pellagra prevention)
• Skin barrier and cellular energy
• Lipid management (prescription niacin—not supplements)


additional medications

• Lifestyle and prescription therapies for lipids
• Omega‑3s
• Dietary approaches (Portfolio/Mediterranean)

medication risks

• Hepatotoxicity at high doses
• Worsened glucose control/gout
• Flushing/pruritus with nicotinic acid

side effects

• Flushing
• Itching
• GI upset
• Headache

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FAQs

Q: Flush vs no‑flush?
A: Niacin (nicotinic acid) flushes; niacinamide does not but doesn’t improve lipids.

Q: Liver safety?
A: High doses can injure the liver—avoid megadoses without care.

Q: Glucose/uric acid?
A: High doses can raise both—monitor if diabetic or with gout.

Q: Interactions?
A: With statins, raises myopathy risk—medical supervision needed.

Q: FDA approval?
A: Supplements aren’t FDA‑approved to treat disease.

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